<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level2" level="2" version="1">
<model metaid="Ec_core" id="Ec_core">
<annotation/>
<listOfUnitDefinitions>
<unitDefinition metaid="substance" id="substance" name="substance">
<listOfUnits>
<unit metaid="CDMT00344" kind="mole"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="volume" id="volume" name="volume">
<listOfUnits>
<unit metaid="CDMT00345" kind="litre"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="area" id="area" name="area">
<listOfUnits>
<unit metaid="CDMT00346" kind="metre" exponent="2"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="length" id="length" name="length">
<listOfUnits>
<unit metaid="CDMT00347" kind="metre"/>
</listOfUnits>
</unitDefinition>
<unitDefinition metaid="time" id="time" name="time">
<listOfUnits>
<unit metaid="CDMT00348" kind="second"/>
</listOfUnits>
</unitDefinition>
</listOfUnitDefinitions>
<listOfCompartments>
<compartment metaid="default" id="default" size="1" units="volume"/>
</listOfCompartments>
<listOfSpecies>
<species metaid="M_h_c" id="M_h_c" name="M_h_c" compartment="default" initialConcentration="0.0221" charge="0">
<annotation/>
</species>
<species metaid="M_glc_D_e" id="M_glc_D_e" name="M_glc_D_e" compartment="default" initialConcentration="0.05587" charge="0">
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</species>
<species metaid="M_adp_c" id="M_adp_c" name="M_adp_c" compartment="default" initialConcentration="0.582" charge="0">
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</species>
<species metaid="M_etoh_c" id="M_etoh_c" name="M_etoh_c" compartment="default" initialConcentration="0.0221" charge="0">
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</species>
<species metaid="M_f6p_c" id="M_f6p_c" name="M_f6p_c" compartment="default" initialConcentration="0.6" charge="0">
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</species>
<species metaid="M_r5p_c" id="M_r5p_c" name="M_r5p_c" compartment="default" initialConcentration="0.398" charge="0">
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</species>
<species metaid="M_oaa_c" id="M_oaa_c" name="M_oaa_c" compartment="default" initialConcentration="0.241" charge="0">
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</species>
<species metaid="M_nadp_c" id="M_nadp_c" name="M_nadp_c" compartment="default" initialConcentration="0.195" charge="0">
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</species>
<species metaid="M_ru5p_D_c" id="M_ru5p_D_c" name="M_ru5p_D_c" compartment="default" initialConcentration="0.111" charge="0">
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</species>
<species metaid="M_mal_L_c" id="M_mal_L_c" name="M_mal_L_c" compartment="default" initialConcentration="0.3413" charge="0">
<annotation/>
</species>
<species metaid="M_atp_c" id="M_atp_c" name="M_atp_c" compartment="default" initialAmount="4.27" hasOnlySubstanceUnits="true" charge="0">
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</species>
<species metaid="M_akg_e" id="M_akg_e" name="M_akg_e" compartment="default" initialConcentration="0.0011" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_2pg_c" id="M_2pg_c" name="M_2pg_c" compartment="default" initialConcentration="0.399" charge="0">
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</species>
<species metaid="M_o2_c" id="M_o2_c" name="M_o2_c" compartment="default" initialConcentration="5.33" charge="0">
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</species>
<species metaid="M_icit_c" id="M_icit_c" name="M_icit_c" compartment="default" initialConcentration="0.21" charge="0">
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</species>
<species metaid="M_fdp_c" id="M_fdp_c" name="M_fdp_c" compartment="default" initialConcentration="0.272" charge="0">
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</species>
<species metaid="M_for_e" id="M_for_e" name="M_for_e" compartment="default" initialConcentration="0" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_ac_e" id="M_ac_e" name="M_ac_e" compartment="default" initialConcentration="0.00479" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_q8_c" id="M_q8_c" name="M_q8_c" compartment="default" initialConcentration="0.0221" charge="0">
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</species>
<species metaid="M_actp_c" id="M_actp_c" name="M_actp_c" compartment="default" initialConcentration="0.4" charge="0">
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</species>
<species metaid="M_fum_e" id="M_fum_e" name="M_fum_e" compartment="default" initialConcentration="0" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_lac_D_c" id="M_lac_D_c" name="M_lac_D_c" compartment="default" initialConcentration="0.001" charge="0">
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</species>
<species metaid="M_o2_e" id="M_o2_e" name="M_o2_e" compartment="default" initialConcentration="5.33" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_nad_c" id="M_nad_c" name="M_nad_c" compartment="default" initialConcentration="1.47" charge="0">
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</species>
<species metaid="M_q8h2_c" id="M_q8h2_c" name="M_q8h2_c" compartment="default" initialConcentration="0.0221" charge="0">
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</species>
<species metaid="M_fadh2_c" id="M_fadh2_c" name="M_fadh2_c" compartment="default" initialConcentration="0.0221" charge="0">
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</species>
<species metaid="M_nadh_c" id="M_nadh_c" name="M_nadh_c" compartment="default" initialConcentration="0.0934" charge="0">
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</species>
<species metaid="M_g6p_c" id="M_g6p_c" name="M_g6p_c" compartment="default" initialConcentration="3.48" charge="0">
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</species>
<species metaid="M_h2o_c" id="M_h2o_c" name="M_h2o_c" compartment="default" initialConcentration="39000" charge="0">
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</species>
<species metaid="M_nadph_c" id="M_nadph_c" name="M_nadph_c" compartment="default" initialConcentration="0.062" charge="0">
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</species>
<species metaid="M_co2_c" id="M_co2_c" name="M_co2_c" compartment="default" initialConcentration="0.0221" charge="0">
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</species>
<species metaid="M_h_e" id="M_h_e" name="M_h_e" compartment="default" initialConcentration="1" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_h2o_e" id="M_h2o_e" name="M_h2o_e" compartment="default" initialConcentration="39000" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_lac_D_e" id="M_lac_D_e" name="M_lac_D_e" compartment="default" initialConcentration="0.001004" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_amp_c" id="M_amp_c" name="M_amp_c" compartment="default" initialConcentration="0.955" charge="0">
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</species>
<species metaid="M_etoh_e" id="M_etoh_e" name="M_etoh_e" compartment="default" initialConcentration="0" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_xu5p_D_c" id="M_xu5p_D_c" name="M_xu5p_D_c" compartment="default" initialConcentration="0.138" charge="0">
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</species>
<species metaid="M_pep_c" id="M_pep_c" name="M_pep_c" compartment="default" initialConcentration="2.67" charge="0">
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</species>
<species metaid="M_co2_e" id="M_co2_e" name="M_co2_e" compartment="default" initialConcentration="1" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_ac_c" id="M_ac_c" name="M_ac_c" compartment="default" initialConcentration="0.36" charge="0">
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</species>
<species metaid="M_pyr_c" id="M_pyr_c" name="M_pyr_c" compartment="default" initialConcentration="2.67" charge="0">
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</species>
<species metaid="M_accoa_c" id="M_accoa_c" name="M_accoa_c" compartment="default" initialConcentration="0.2473" charge="0">
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</species>
<species metaid="M_6pgc_c" id="M_6pgc_c" name="M_6pgc_c" compartment="default" initialConcentration="0.808" charge="0">
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</species>
<species metaid="M_6pgl_c" id="M_6pgl_c" name="M_6pgl_c" compartment="default" initialConcentration="0.0221" charge="0">
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</species>
<species metaid="M_coa_c" id="M_coa_c" name="M_coa_c" compartment="default" initialConcentration="0.07298" charge="0">
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</species>
<species metaid="M_glx_c" id="M_glx_c" name="M_glx_c" compartment="default" initialConcentration="0.001" charge="0">
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<species metaid="M_3pg_c" id="M_3pg_c" name="M_3pg_c" compartment="default" initialConcentration="2.13" charge="0">
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<species metaid="M_pyr_e" id="M_pyr_e" name="M_pyr_e" compartment="default" initialConcentration="0.001288" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_for_c" id="M_for_c" name="M_for_c" compartment="default" initialConcentration="0.0221" charge="0">
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<species metaid="M_pi_c" id="M_pi_c" name="M_pi_c" compartment="default" initialConcentration="1" charge="0">
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</species>
<species metaid="M_succ_e" id="M_succ_e" name="M_succ_e" compartment="default" initialConcentration="0.006821" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_pi_e" id="M_pi_e" name="M_pi_e" compartment="default" initialConcentration="1" boundaryCondition="true" charge="0">
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</species>
<species metaid="M_fad_c" id="M_fad_c" name="M_fad_c" compartment="default" initialConcentration="0.01514" charge="0">
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</species>
</listOfSpecies>
<listOfReactions>
<reaction metaid="R_D_LACt2" id="R_D_LACt2" name="R_D_LACt2">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00001" species="M_lac_D_e"/>
<speciesReference metaid="CDMT00002" species="M_h_e"/>
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<listOfProducts>
<speciesReference metaid="CDMT00003" species="M_h_c"/>
<speciesReference metaid="CDMT00004" species="M_lac_D_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_SUCD4" id="R_SUCD4" name="R_SUCD4">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00005" species="M_fadh2_c"/>
<speciesReference metaid="CDMT00006" species="M_q8_c"/>
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<listOfProducts>
<speciesReference metaid="CDMT00007" species="M_q8h2_c"/>
<speciesReference metaid="CDMT00008" species="M_fad_c"/>
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</reaction>
<reaction metaid="R_PPCK" id="R_PPCK" name="R_PPCK" reversible="false">
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<listOfReactants>
<speciesReference metaid="CDMT00009" species="M_oaa_c"/>
<speciesReference metaid="CDMT00010" species="M_atp_c"/>
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<listOfProducts>
<speciesReference metaid="CDMT00011" species="M_pep_c"/>
<speciesReference metaid="CDMT00012" species="M_adp_c"/>
<speciesReference metaid="CDMT00013" species="M_co2_c"/>
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</reaction>
<reaction metaid="R_LDH_D" id="R_LDH_D" name="R_LDH_D">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00014" species="M_nad_c"/>
<speciesReference metaid="CDMT00015" species="M_lac_D_c"/>
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<listOfProducts>
<speciesReference metaid="CDMT00016" species="M_h_c"/>
<speciesReference metaid="CDMT00017" species="M_nadh_c"/>
<speciesReference metaid="CDMT00018" species="M_pyr_c"/>
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</reaction>
<reaction metaid="R_CYTBD" id="R_CYTBD" name="R_CYTBD" reversible="false">
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<speciesReference metaid="CDMT00019" species="M_h_c" stoichiometry="2"/>
<speciesReference metaid="CDMT00020" species="M_q8h2_c"/>
<speciesReference metaid="CDMT00021" species="M_o2_c" stoichiometry="0.5"/>
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<speciesReference metaid="CDMT00022" species="M_h2o_c"/>
<speciesReference metaid="CDMT00023" species="M_q8_c"/>
<speciesReference metaid="CDMT00024" species="M_h_e" stoichiometry="2"/>
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<reaction metaid="R_PDH" id="R_PDH" name="R_PDH" reversible="false">
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<speciesReference metaid="CDMT00025" species="M_nad_c"/>
<speciesReference metaid="CDMT00026" species="M_pyr_c"/>
<speciesReference metaid="CDMT00027" species="M_coa_c"/>
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<speciesReference metaid="CDMT00029" species="M_co2_c"/>
<speciesReference metaid="CDMT00030" species="M_accoa_c"/>
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<reaction metaid="R_PPS" id="R_PPS" name="R_PPS" reversible="false">
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<speciesReference metaid="CDMT00033" species="M_pyr_c"/>
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<reaction metaid="rR_RPE" id="rR_RPE" name="rR_RPE">
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<speciesReference metaid="CDMT00049" species="M_xu5p_D_c"/>
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<reaction metaid="R_PTAr" id="R_PTAr" name="R_PTAr">
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<speciesReference metaid="CDMT00051" species="M_pi_c"/>
<speciesReference metaid="CDMT00052" species="M_accoa_c"/>
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<speciesReference metaid="CDMT00053" species="M_actp_c"/>
<speciesReference metaid="CDMT00054" species="M_coa_c"/>
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<reaction metaid="rR_RPI" id="rR_RPI" name="rR_RPI">
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<speciesReference metaid="CDMT00055" species="M_ru5p_D_c"/>
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<speciesReference metaid="CDMT00056" species="M_r5p_c"/>
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<reaction metaid="rR_CO2t" id="rR_CO2t" name="rR_CO2t">
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<speciesReference metaid="CDMT00063" species="M_co2_c"/>
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<speciesReference metaid="CDMT00064" species="M_co2_e"/>
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<reaction metaid="R_EX_ac_e_" id="R_EX_ac_e_" name="R_EX_ac_e_">
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<speciesReference metaid="CDMT00065" species="M_ac_e"/>
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<reaction metaid="R_ATPM" id="R_ATPM" name="R_ATPM" reversible="false">
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<speciesReference metaid="CDMT00067" species="M_h2o_c"/>
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<speciesReference metaid="CDMT00069" species="M_h_c"/>
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<speciesReference metaid="CDMT00071" species="M_adp_c"/>
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<reaction metaid="M7" id="M7" name="M7" reversible="false">
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<speciesReference metaid="CDMT00087" species="M_3pg_c" stoichiometry="0.415798166653008"/>
<speciesReference metaid="CDMT00088" species="M_h_c" stoichiometry="0.972034477430443"/>
<speciesReference metaid="CDMT00089" species="M_nadh_c" stoichiometry="0.75309193904818"/>
<speciesReference metaid="CDMT00090" species="M_pi_c" stoichiometry="0.0219839390723505"/>
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<speciesReference metaid="CDMT00092" species="M_mal_L_c" stoichiometry="0.271324022971344"/>
<speciesReference metaid="CDMT00093" species="M_nadph_c" stoichiometry="0.0470281830752685"/>
<speciesReference metaid="CDMT00094" species="M_fadh2_c" stoichiometry="0.271324022971344"/>
<speciesReference metaid="CDMT00095" species="M_co2_c" stoichiometry="0.556761621721661"/>
<speciesReference metaid="CDMT00096" species="M_coa_c" stoichiometry="0.0490266561353607"/>
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<reaction metaid="rR_EX_o2_e_" id="rR_EX_o2_e_" name="rR_EX_o2_e_">
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<speciesReference metaid="CDMT00103" species="M_o2_e"/>
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<reaction metaid="R_EX_etoh_e_" id="R_EX_etoh_e_" name="R_EX_etoh_e_">
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<speciesReference metaid="CDMT00104" species="M_etoh_e"/>
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<speciesReference metaid="CDMT00109" species="M_h2o_c"/>
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<speciesReference metaid="CDMT00110" species="M_pi_c"/>
<speciesReference metaid="CDMT00111" species="M_f6p_c"/>
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<reaction metaid="R_GND" id="R_GND" name="R_GND" reversible="false">
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<speciesReference metaid="CDMT00112" species="M_nadp_c"/>
<speciesReference metaid="CDMT00113" species="M_6pgc_c"/>
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<speciesReference metaid="CDMT00114" species="M_ru5p_D_c"/>
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<speciesReference metaid="CDMT00116" species="M_co2_c"/>
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<reaction metaid="R_FORt" id="R_FORt" name="R_FORt">
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<speciesReference metaid="CDMT00119" species="M_for_e"/>
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<listOfProducts>
<speciesReference metaid="CDMT00120" species="M_for_c"/>
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<reaction metaid="R_ATPS4r" id="R_ATPS4r" name="R_ATPS4r">
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<speciesReference metaid="CDMT00121" species="M_pi_c"/>
<speciesReference metaid="CDMT00122" species="M_adp_c"/>
<speciesReference metaid="CDMT00123" species="M_h_e" stoichiometry="4"/>
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<speciesReference metaid="CDMT00124" species="M_h_c" stoichiometry="3"/>
<speciesReference metaid="CDMT00125" species="M_h2o_c"/>
<speciesReference metaid="CDMT00126" species="M_atp_c"/>
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<reaction metaid="R_ENO" id="R_ENO" name="R_ENO">
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<speciesReference metaid="CDMT00131" species="M_2pg_c"/>
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<listOfProducts>
<speciesReference metaid="CDMT00132" species="M_pep_c"/>
<speciesReference metaid="CDMT00133" species="M_h2o_c"/>
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</reaction>
<reaction metaid="R_ETOHt2r" id="R_ETOHt2r" name="R_ETOHt2r">
<annotation/>
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<speciesReference metaid="CDMT00134" species="M_h_e"/>
<speciesReference metaid="CDMT00135" species="M_etoh_e"/>
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<listOfProducts>
<speciesReference metaid="CDMT00136" species="M_h_c"/>
<speciesReference metaid="CDMT00137" species="M_etoh_c"/>
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</reaction>
<reaction metaid="R_EX_h_e_" id="R_EX_h_e_" name="R_EX_h_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00142" species="M_h_e"/>
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</reaction>
<reaction metaid="R_G6PDH2r" id="R_G6PDH2r" name="R_G6PDH2r">
<annotation/>
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<speciesReference metaid="CDMT00146" species="M_nadp_c"/>
<speciesReference metaid="CDMT00147" species="M_g6p_c"/>
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<listOfProducts>
<speciesReference metaid="CDMT00148" species="M_h_c"/>
<speciesReference metaid="CDMT00149" species="M_nadph_c"/>
<speciesReference metaid="CDMT00150" species="M_6pgl_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_EX_h2o_e_" id="R_EX_h2o_e_" name="R_EX_h2o_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00151" species="M_h2o_e"/>
</listOfReactants>
</reaction>
<reaction metaid="R_EX_succ_e_" id="R_EX_succ_e_" name="R_EX_succ_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00153" species="M_succ_e"/>
</listOfReactants>
</reaction>
<reaction metaid="M3" id="M3" name="M3" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00155" species="M_oaa_c"/>
<speciesReference metaid="CDMT00156" species="M_h2o_c"/>
<speciesReference metaid="CDMT00157" species="M_accoa_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00158" species="M_icit_c"/>
<speciesReference metaid="CDMT00159" species="M_h_c"/>
<speciesReference metaid="CDMT00160" species="M_coa_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_O2t" id="R_O2t" name="R_O2t">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00167" species="M_o2_e"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00168" species="M_o2_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_ACKr" id="R_ACKr" name="R_ACKr">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00171" species="M_ac_c"/>
<speciesReference metaid="CDMT00172" species="M_atp_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00173" species="M_adp_c"/>
<speciesReference metaid="CDMT00174" species="M_actp_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_EX_pyr_e_" id="R_EX_pyr_e_" name="R_EX_pyr_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00177" species="M_pyr_e"/>
</listOfReactants>
</reaction>
<reaction metaid="R_PPC" id="R_PPC" name="R_PPC" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00179" species="M_pep_c"/>
<speciesReference metaid="CDMT00180" species="M_h2o_c"/>
<speciesReference metaid="CDMT00181" species="M_co2_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00182" species="M_h_c"/>
<speciesReference metaid="CDMT00183" species="M_pi_c"/>
<speciesReference metaid="CDMT00184" species="M_oaa_c"/>
</listOfProducts>
</reaction>
<reaction metaid="rR_H2Ot" id="rR_H2Ot" name="rR_H2Ot">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00185" species="M_h2o_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00186" species="M_h2o_e"/>
</listOfProducts>
</reaction>
<reaction metaid="R_PYK" id="R_PYK" name="R_PYK" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00187" species="M_h_c"/>
<speciesReference metaid="CDMT00188" species="M_pep_c"/>
<speciesReference metaid="CDMT00189" species="M_adp_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00190" species="M_atp_c"/>
<speciesReference metaid="CDMT00191" species="M_pyr_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_EX_for_e_" id="R_EX_for_e_" name="R_EX_for_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00196" species="M_for_e"/>
</listOfReactants>
</reaction>
<reaction metaid="R_ADK1" id="R_ADK1" name="R_ADK1">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00198" species="M_atp_c"/>
<speciesReference metaid="CDMT00199" species="M_amp_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00200" species="M_adp_c" stoichiometry="2"/>
</listOfProducts>
</reaction>
<reaction metaid="R_MALS" id="R_MALS" name="R_MALS" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00207" species="M_glx_c"/>
<speciesReference metaid="CDMT00208" species="M_h2o_c"/>
<speciesReference metaid="CDMT00209" species="M_accoa_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00210" species="M_h_c"/>
<speciesReference metaid="CDMT00211" species="M_mal_L_c"/>
<speciesReference metaid="CDMT00212" species="M_coa_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_GLCpts" id="R_GLCpts" name="R_GLCpts" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00213" species="M_pep_c"/>
<speciesReference metaid="CDMT00214" species="M_glc_D_e"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00215" species="M_g6p_c"/>
<speciesReference metaid="CDMT00216" species="M_pyr_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_THD2" id="R_THD2" name="R_THD2" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00219" species="M_nadh_c"/>
<speciesReference metaid="CDMT00220" species="M_nadp_c"/>
<speciesReference metaid="CDMT00221" species="M_h_e" stoichiometry="2"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00222" species="M_h_c" stoichiometry="2"/>
<speciesReference metaid="CDMT00223" species="M_nad_c"/>
<speciesReference metaid="CDMT00224" species="M_nadph_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_EX_co2_e_" id="R_EX_co2_e_" name="R_EX_co2_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00227" species="M_co2_e"/>
</listOfReactants>
</reaction>
<reaction metaid="rR_EX_pi_e_" id="rR_EX_pi_e_" name="rR_EX_pi_e_">
<annotation/>
<listOfProducts>
<speciesReference metaid="CDMT00234" species="M_pi_e"/>
</listOfProducts>
</reaction>
<reaction metaid="R_ME2" id="R_ME2" name="R_ME2" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00237" species="M_nadp_c"/>
<speciesReference metaid="CDMT00238" species="M_mal_L_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00239" species="M_nadph_c"/>
<speciesReference metaid="CDMT00240" species="M_co2_c"/>
<speciesReference metaid="CDMT00241" species="M_pyr_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_EX_akg_e_" id="R_EX_akg_e_" name="R_EX_akg_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00242" species="M_akg_e"/>
</listOfReactants>
</reaction>
<reaction metaid="R_ACt2r" id="R_ACt2r" name="R_ACt2r">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00244" species="M_ac_e"/>
<speciesReference metaid="CDMT00245" species="M_h_e"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00246" species="M_h_c"/>
<speciesReference metaid="CDMT00247" species="M_ac_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_MDH" id="R_MDH" name="R_MDH">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00252" species="M_nad_c"/>
<speciesReference metaid="CDMT00253" species="M_mal_L_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00254" species="M_h_c"/>
<speciesReference metaid="CDMT00255" species="M_nadh_c"/>
<speciesReference metaid="CDMT00256" species="M_oaa_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_PGI" id="R_PGI" name="R_PGI">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00259" species="M_g6p_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00260" species="M_f6p_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_PFL" id="R_PFL" name="R_PFL" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00261" species="M_pyr_c"/>
<speciesReference metaid="CDMT00262" species="M_coa_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00263" species="M_for_c"/>
<speciesReference metaid="CDMT00264" species="M_accoa_c"/>
</listOfProducts>
</reaction>
<reaction metaid="rR_PIt" id="rR_PIt" name="rR_PIt">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00276" species="M_pi_e"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00277" species="M_pi_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_ME1" id="R_ME1" name="R_ME1" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00278" species="M_nad_c"/>
<speciesReference metaid="CDMT00279" species="M_mal_L_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00280" species="M_nadh_c"/>
<speciesReference metaid="CDMT00281" species="M_co2_c"/>
<speciesReference metaid="CDMT00282" species="M_pyr_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_EX_lac_D_e_" id="R_EX_lac_D_e_" name="R_EX_lac_D_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00283" species="M_lac_D_e"/>
</listOfReactants>
</reaction>
<reaction metaid="R_PFK" id="R_PFK" name="R_PFK" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00293" species="M_atp_c"/>
<speciesReference metaid="CDMT00294" species="M_f6p_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00295" species="M_h_c"/>
<speciesReference metaid="CDMT00296" species="M_fdp_c"/>
<speciesReference metaid="CDMT00297" species="M_adp_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_PGL" id="R_PGL" name="R_PGL" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00298" species="M_h2o_c"/>
<speciesReference metaid="CDMT00299" species="M_6pgl_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00300" species="M_h_c"/>
<speciesReference metaid="CDMT00301" species="M_6pgc_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_NADTRHD" id="R_NADTRHD" name="R_NADTRHD" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00305" species="M_nad_c"/>
<speciesReference metaid="CDMT00306" species="M_nadph_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00307" species="M_nadh_c"/>
<speciesReference metaid="CDMT00308" species="M_nadp_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_ADHEr" id="R_ADHEr" name="R_ADHEr">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00309" species="M_h_c" stoichiometry="2"/>
<speciesReference metaid="CDMT00310" species="M_nadh_c" stoichiometry="2"/>
<speciesReference metaid="CDMT00311" species="M_accoa_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00312" species="M_nad_c" stoichiometry="2"/>
<speciesReference metaid="CDMT00313" species="M_etoh_c"/>
<speciesReference metaid="CDMT00314" species="M_coa_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_PYRt2r" id="R_PYRt2r" name="R_PYRt2r">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00326" species="M_pyr_e"/>
<speciesReference metaid="CDMT00327" species="M_h_e"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00328" species="M_h_c"/>
<speciesReference metaid="CDMT00329" species="M_pyr_c"/>
</listOfProducts>
</reaction>
<reaction metaid="R_NADH11" id="R_NADH11" name="R_NADH11" reversible="false">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00330" species="M_h_c" stoichiometry="3"/>
<speciesReference metaid="CDMT00331" species="M_nadh_c"/>
<speciesReference metaid="CDMT00332" species="M_q8_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00333" species="M_nad_c"/>
<speciesReference metaid="CDMT00334" species="M_q8h2_c"/>
<speciesReference metaid="CDMT00335" species="M_h_e" stoichiometry="2"/>
</listOfProducts>
</reaction>
<reaction metaid="rR_PGM" id="rR_PGM" name="rR_PGM">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00336" species="M_3pg_c"/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid="CDMT00337" species="M_2pg_c"/>
</listOfProducts>
</reaction>
<reaction metaid="rR_EX_glc_e_" id="rR_EX_glc_e_" name="rR_EX_glc_e_" reversible="false">
<annotation/>
<listOfProducts>
<speciesReference metaid="CDMT00339" species="M_glc_D_e"/>
</listOfProducts>
</reaction>
<reaction metaid="R_EX_fum_e_" id="R_EX_fum_e_" name="R_EX_fum_e_">
<annotation/>
<listOfReactants>
<speciesReference metaid="CDMT00342" species="M_fum_e"/>
</listOfReactants>
</reaction>
</listOfReactions>
</model>
</sbml>
